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Cancer Treatment / Drug / Skin Issue Chart

Each of the various treatments (chemotherapy, targeted therapy, radiation therapy) can have a different impact on your skin.  The best way to take control over your skin is to knowing the potential side effects you may face and to follow a good preventative skin care regimen even before any symptoms arise.

Browse the chart below to find your treatment – along with a list of potential skin reactions and regimens that you may find useful.

Treatment/
Drug Type
Drug Brand Name (generic name)Potential Adverse Skin Issue Skin Care Regimens & Solutions
Epidermal growth factor receptor (EGFR) inhibitors
  • Iressa (Gefitinib)
  • Erbitux (Cetuximab)
  • Tarceva (Erlotinib)
  • Vectibix (Panitumumab)
  • Tykerb (Lapatinib)
  • Combined EGFR/HER2 antagonists
  • Face (EFGR) rash
  • xerosis (dry skin)
  • pruritus (itching)
  • erythema
  • papules/pustules
  • telangiectasia
  • fissures
  • alopecia
  • discolored or bumpy nails
  • Face Regimens
  • Dry / Itchy Skin Regimens
Multikinase inhibitors
  • Gleevec (Imatinib)
  • Sprycel (Dasatinib)
  • Tasigna (Nilotinib)
  • Nexavar (Sorafenib)
  • Sutent (Sunitinib)
  • Hand-foot syndrome
  • Face (EGFR) rash
  • pruritus (itching)
  • xerosis (dry skin)
  • facial erythema
  • scalp dysesthesia
  • subungual splinter hemorrhages
  • skin discoloration
  • bruising
  • thinning of skin
  • Hand & Foot Regimens
  • Face Regimens
  • Dry / Itchy Skin Regimens
Alkylating agents
  • Myleran (Busulfan)
  • Eloxatin (Oxaliplatin Melphalan)
  • Temodar (Temozolomide)
  • Paraplatin (Carboplatin)
  • Thioplex (Thiotepa)
  • Mustargen (Mechlorethamine)
  • Leukeran (Chlorambucil)
  • Zanosar (Streptozocin)
  • Platinol (Cisplatin)
  • Semustine (Methyl-CCNU)
  • Endoxana (Cyclophosphamide)
  • DTIC, DTIC - Dome (Dacarbazine)
  • Ifex (Ifosfamide)
  • Nail issues (paronychia)
  • xerosis (dry skin)
  • pruritus (itching)
  • mucositis
  • flushing
  • facial erythema
  • alopecia
  • pigmented bands on nails and teeth
  • Hand/Nail Regimens
  • Dry / Itchy Skin Regimens
Spindle inhibitors
  • Taxotere (Docetaxel)
  • Texol (Paclitaxel)
  • Navelbine (Vinorelbine)
  • Camptosar (Irinotecan)
  • Hycamtin (Topotecan)
  • Velban (Vinblastine)
  • Oncovin (Vincristine)
  • Vepesid (Etoposide)
  • Hand-foot syndrome
  • xerosis (dry skin)
  • pruritus (itching)
  • dermatitis
  • edema
  • mucositis
  • Hand & Foot Regimens
  • Dry & Itchy Skin Regimens
Antimetabolites
  • Fludara (Fludarabine)
  • Leustation (Cladribine)
  • Xeloda (Capecitabine)
  • Clolar (Clofarabine)
  • Depocyt (Cytarabine)
  • FUDR (Floxuridine)
  • Hyrdea (Hydroxyurea)
  • Arrano (Nelarabine)
  • Nipent (Pentostatin)
  • Rheumatrex (Methotrexate)
  • Purinethol (Mercaptopurine)
  • Tabloid (Thioguanine)
  • Adrucil (5-fluorouracil)
  • Uftoral (Tegafur)
  • Gemzar (Gemcitabine)
  • Alimta (Pemetrexed)
  • Hand-foot syndrome
  • pruritus (itching)
  • xerosis (dry skin)
  • edema
  • facial flushing
  • photosensitivity
  • mucositis
  • Hand & Foot Regimens
  • Dry & Itchy Skin Regimens
Antitumor antibiotics
  • Blenoxane (Bleomycin)
  • Ellence (Epirubicin)
  • Idamycin (Idarubicin)
  • Mithracin (Plicamycin)
  • Novatrone (Mitoxantrone)
  • Cosmegen (Dactinomycin)
  • Cerubidine (Daunorubicin or Rubidomycin)
  • Hand-foot syndrome
  • pruritus (itching)
  • xerosis (dry skin)
  • Rash (flagellate hyperpigmentation)
  • mucositis
  • Hand & Foot Regimens
  • Dry & Itchy Skin Regimens
Antiangiogenesis
  • Auasin (Bevacizumab)
  • Xerosis (dry skin)
  • mucositis
  • flushing
  • sores on mouth or lips
  • Dry & Itchy Skin Regimens
Corticosteroid hormones/other
  • Deltasone (Prednisone)
  • Orasone (Prednisone)
  • Prednicen-M (Prednisone)
  • Liquid Pred (Prednisone)
  • Bruising
  • fungal infections (white patches in mouth, vagina)
 
Hormones/aromatase inhibitors
  • Cytadren (Aminoglutethimide)
  • Zevalin (Ibritumomab)
  • Casodex (Bicalutamide)
  • Herceptin (Trastuzumab)
  • Eulexin (Flutamide)
  • Faslodex (Fulvestrant)
  • Bexxar (Tositumomab)
  • Nolvadex (Tamoxifen)
  • Femara (Letrozole)
  • Zoladex (Goserelin)
  • Lupron (Leuprolide)
  • Megace ES (Megestrol Acetate)
  • Hot flashes
  • edema
  • angioedema
  • erythema
  • rash
  • flushing
 
Radiation
  • External beam therapy
  • External Beam Radiation
  • External Radiation Therapy
  • Novalis Tx®, Varian Medical Systems, Inc. and BrainLab, Inc. (Intensity modulated radiation therapy)
  • Synergy S®, Elekta, Inc. (Intensity modulated radiation therapy)
  • CyberKnife®, Accuray, Inc. (Intensity modulated radiation therapy)
  • stereotactic radiosurgery (with gamma knife)
  • Radiation dermatitis
  • dry desquamation
  • Cooling Regimens
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