Fight skin-related side effects of chemo and radiation with some intense hydration! Fight back with Lindi Soothing Balm!
Cancer Resources for Skincare
Northwestern University Clinical Study Finds Lindi Skin Improves Quality of Life for Cancer Patients
Supportive Care in Cancer
Volume 19, Number 4, 545-554, DOI: 10.1007/s00520-010-0851-8Open Access
Skin care management in cancer patients: an evaluation of quality of life and tolerability
Ann Cameron Haley, Cara Calahan, Mona Gandhi, Dennis P. West, Alfred Rademaker and Mario E. Lacouture
The objective of this study is to evaluate quality of life (QoL) and tolerability of three articles specifically developed for cancer skin care management (skin moisturizer, face moisturizer, and face wash).
Participants were cancer patients (n = 99) receiving systemic anticancer therapies and/or radiotherapy at Northwestern University. Subjects were assessed at the initial visit for adverse skin reactions based on the National Cancer Institute’s Common Terminology Criteria for Adverse Events version 3.0 and completed the Skindex-16 questionnaire, a self-reported dermatology-specific QoL instrument. All subjects were provided with three test articles and were instructed to use each test article once daily for 4 weeks. At the 4-week follow-up (n = 77), the Skindex-16 was readministered, adverse skin reactions were assessed, and tolerability questionnaires were administered for each article used.
Dry skin, hand–foot skin reaction (HFSR), and skin rash (dermatitis) decreased significantly from baseline to follow-up. Presence of nail changes, skin rash (desquamation), and acne/acneiform eruptions did not significantly change from baseline. Subjects had a significantly lower mean overall Skindex-16 score at 4-week follow-up when compared to baseline. Most patients rated their overall experience with each test article as good or very good (highest rating).
Skin care in cancer patients is suboptimal in part due to a lack of products and knowledge specific for this population. Our findings suggest that Quality of Life improves with test article use, all of which were rated as good/very good for tolerability. Moreover, skin toxicity as manifested by dry skin, hand-foot skin reaction, and skin rash (dermatitis) were decreased with use of test articles within 4 weeks.
To read the entire article go to this page:
Chicago, IL (Northwestern University - Original Article) –March 25th, 2010
Ann Cameron Haley, Cara Calahan, Mona Gandhi, Dennis P. West, Alfred Rademaker and Mario E. Lacouture
Thursday, March 25th, 2010
Skin care in cancer patients is suboptimal in part due to a lack of products and knowledge specific for this population. Our findings suggest that QoL improves with test article use, all of which were rated as good/very good for tolerability. Moreover, skin toxicity as manifested by dry skin, hand-foot skin reaction, and skin rash (dermatitis) were decreased with use of test articles within 4 weeks.
Dermatologic toxicities are common side effects associated with anticancer treatments, and these adverse events often negatively impact a patient’s quality of life and willingness to continue with treatment . Management of these events in cancer patients is suboptimal in part due to the lack of products specifically designed for this patient population. In seeking to investigate the tolerability and effects on quality of life for products designed for cancer skin care management, these findings suggest that quality of life, as measured by Skindex-16, improves with products specifically designed for cancer skin care management. Moreover, the severity of skin toxicity graded according to CTCAE decreases within 1-month use of products specifically designed for cancer skin care management, and dermatology quality of life significantly improves as early as 1 month for individual domains (symptoms, emotions, functions).
This study demonstrates that products specifically designed for cancer skin care management improve skin-related quality of life. Moreover, patients with rosacea and rosacea-like erythematous facial skin are often very sensitive to skin care products that can worsen inflammation and produce irritation . This study demonstrated cancer patients with pre-existing rosacea tolerate test articles A, B, and C. Maintenance of cutaneous integrity during cancer treatments with the use of moisturizers may aid in mitigating dry skin, which may be associated with pruritus and infections, minimizing these comorbidities [17, 18].
In summary, specifically tailored skin care management for cancer patients is well tolerated by patients currently undergoing anticancer therapy or radiation, and a majority of subjects report that such therapies are better than previous regimens used. A majority of participants also report improved dermatology QoL. Previous studies indicate that dermatology QoL rebounds within 4 months of completion of anticancer regiments, making it important for patients to receive interventions during anticancer therapy and the immediate 4-month follow-up period .
Advance knowledge of side effects and proactive management approaches have been shown to decrease anxiety, improve adherence to cancer treatment, and improve QoL and patient outcomes . Studies suggest that anticancer therapy side effects are less anxiety provoking when anticipated . If patients engage in anticipatory coping, a mechanism involving “affective and behavioral rehearsal,” patients feel in control when toxicities resulting from cancer treatments arise . A cancer skin care management program fulfills patient engagement of anticipatory coping in order to optimally anticipate and control cutaneous side effects associated with anticancer therapy.
Acknowledgments We are grateful to Lindi®Skin for providing test articles. M.E.L. is supported by a Zell Scholarship from the Robert H Lurie Comprehensive Cancer Center and a Dermatology Foundation Career Development Award.
Health Talk Radio with Mealine Cole M.S.
Listen to the Full Interview Here
Excerpt from Health Radio: “A recent survey by CancerCare showed that nearly 80% of people with cancer were concerned about the impact skin effects had on their quality of life during treatment. Unfortunately, many people don't realize the issues created by skin effects. In a first-ever initiative, renowned health-care providers identify and describe how cancer treatment-related toxicities have a negative effect on quality of life from the perspective of patients and survivors.
Advances in cancer treatments have greatly improved survival rates for many diagnoses. Yet, the lingering side effects of many cancer treatments have only recently begun to be addressed.
For Lindi Snider, the creation of Lindi Skin started with her personal experience watching friends go through cancer treatment. They expected the nausea, fatigue and hair loss associated with chemotherapy and radiation therapy, but they were not aware of the impact that these therapies would have on their skin. In discovering there was not one line of skin care products specifically developed for people with cancer, it occurred to Lindi that someone had to create one.. and so she did. She aligned herself with dermatologists, oncologists, nurses, patients and skincare formulators to create the first and only complete skin care line developed for the unique needs of people with cancer. She comes on the show to discuss her experiences and how they have changed her life.”
New York & Philadelphia (Supportive Care in Cancer) January 6th, 2010
In a first-ever initiative, renowned health-care providers identify and describe how cancer treatment-related toxicities have a negative effect on quality of life from the perspective of patients and survivors. The findings of this study, made possible by CancerCare and Lindi Skin, are now available exclusively from the medical journal, Supportive Care in Cancer, at http://www.springerlink.com/content/9n31658g173g1277/.
“The impact of dermatologic toxicities was found to be unanticipated prior to cancer treatments, to a greater degree than gastrointestinal and constitutional side effects” stated Dr. Mario Lacouture, Associate Attending Physician, Memorial Sloan-Kettering Cancer Center. “Since these events have a negative effect on survivors' lives, pretreatment counseling and effective interventions are vital in order to maximize quality of life and minimize unnecessary treatment interruptions or discontinuations.”
This landmark skincare study was pursued by medical leaders and centers including: Mona Gandhi, Department of Dermatology, Northwestern University’s Feinberg School of Medicine; Karen Oishi, University of Texas, M.D. Anderson Cancer Center, Houston, TX; Beth Zubal, Washington University School of Medicine, St. Louis, MO; and Dr, Mario E. Lacouture SERIES Clinic, Robert H Lurie Comprehensive Cancer Center, Northwestern University’s Feinberg School of Medicine, now at Memorial Sloan-Kettering Cancer Center.
“Advances in cancer treatments have greatly improved survival rates for many diagnoses. Yet, the lingering side effects of many cancer treatments have only recently begun to be addressed,” said Rosalie Canosa, Program Division Director, CancerCare. “This survey breaks new ground in understanding not only the physical but also the psychological impact of these side effects from the patient’s perspective, and what can be done to help alleviate them.”
The results of this breakthrough study released by Supportive Care in Cancer articulate that cancer survivors reported an increased concern regarding dermatologic toxicities, including irritated and dry skin, after receiving their cancer treatment. These events had a negative effect on their lives.
CancerCare is a national nonprofit organization that provides free, professional support services to anyone affected by cancer: people with cancer, caregivers, children, loved ones, and the bereaved. CancerCare programs—including counseling and support groups, education, financial assistance and practical help—are provided by professional oncology social workers and are completely free of charge. Founded in 1944, CancerCare provided individual help to more than 100,000 people last year, in addition to the more than 1 million unique visitors to its websites. Find out more about CancerCare by calling 1-800-813-HOPE (4673) or at www.cancercare.org.
Lindi Skin (www.lindiskin.com ) was created with the counsel of leading dermatologists and oncologists for those suffering the skin side effects of specific cancer therapies. This extensive collection of mild and luxurious serums, lotions and balms is the only full line of skincare products developed to improve the lives of individuals undergoing chemotherapy and radiation therapy.
Press Contact: Leslie Padilla / 610-500-4698 / email@example.com
Transcript of Power Patient webcast with Mario Lacouture, M.D.
The Cancer Skin Care Program at Northwestern
Most everyone knows that today's intense, often, cancer treatment can cause side
effects. Normally there are some side effects, and they can be on your hair, your
skin and your nails, and certainly that can impact a patient's quality of life. Coming
up next on Patient Power is an interview with an expert from Northwestern
Memorial Hospital sharing his knowledge how best to manage these side effects.
Hello and welcome to once again to Patient Power sponsored by Northwestern
Memorial Hospital. I'm Andrew Schorr. Well, we all know that our efforts to beat
cancer with powerful medicines can have side effects that go along with it. Now,
these are side effects that you may experience while you're going through
treatment, or they could be effects that come later, even years later, and so you
need to be mindful of that. Now, the most apparent side effect that many people
are aware of from some cancer drugs is some drugs can you cause you to lose your
hair. I was a leukemia patient, the drugs I took didn't cause that, although I was
bald already, but women who have been treated for breast cancer or kids who are
treated for leukemia may lose their hair, but there also can be effects on your skin
or your nails. And beyond that is some of the newer medicines do have side effects
like this. So newer medicines, even more powerful, but can have some significant
effects on your skin.
And of course the one thing you don't want to have happen during treatment is
have these effects become so great that you need to stop your therapy, in other
words put a stop to the cancer-fighting medicines that you're taking. Well, there is
a doctor at Northwestern, an oncologic dermatologist, who specializes in helping
cancer patients get through all this, stay on their therapy or deal with later effects,
and that is Dr. Mario Lacouture. He's a dermatologist at Northwestern Memorial
Hospital, and he's assistant professor of dermatology at Northwestern University's
Feinberg School of Medicine. Also I should tell you that he is the director of the
cancer skin care program in the department of dermatology at the Robert H. Lurie
Comprehensive Cancer Center at Northwestern. Dr. Lacouture, thank you so much
for being with us. Tell us, this program sounds quite unusual, and I know it was
the first in the country, started just in early 2006. What is this program?
Read the full webcast HERE
Abstract: As inhibitors of the epidermal growth factor receptor (EGFR) become an increasingly common therapeutic option in cancer, appropriate management of their associated toxicities emerges as a critical part of treatment. Cutaneous manifestations, probably linked to the function of the EGFR in epithelial development, are the most common adverse reactions to EGFR inhibition. The key manifestations are follicular eruptions, nail disorders, xerosis, and desquamation. Growing attention continues to be devoted to the analysis of these events, particularly given their potential role as markers of responsiveness to treatment. However, to date, there are few evidence-based guidelines for the appropriate management of these dermatologic events. Multidisciplinary collaboration between oncologists and dermatologists will be required to improve our understanding and optimize the characterization of these skin toxicities, and to design effective management approaches. Read More
published April 20th, 2006
By Kayleen Schaefer
FOR the last seven years that Kairol Rosenthal, 35, has battled thyroid cancer with hormone pills, radiation, surgery and grit, she has had to contend with 101-degree fevers, heart palpitations and a lack of appetite so pronounced she has to force herself to eat.
The hormone therapy, designed to slow tumor growth, leaves red blotches on her face and bone-dry patches along her jaw line, said Ms. Rosenthal, a choreographer and writer in Chicago.
“I have not yet made my peace with having skin that doesn’t look good,” said Ms. Rosenthal, who spends most of her free time hunting for news about thyroid cancer. “I want my skin to look good.”
So Ms. Rosenthal was pleased when she heard an advertisement for Lindi Skin, a skincare line designed for cancer patients, on a radio program called “The Stupid Cancer Show.”
“It’s great someone has cancer patients in mind,” said Ms. Rosenthal, who is writing a book about living with the disease, to be published by Wiley.
She ordered samples of the brand’s face wash and lavender face serum, which, Lindi Skin’s Web site says, “are intended to help individuals feel better, both physically and emotionally and gain a greater degree of control over the side effects they experience during radiation therapy and chemotherapy.”
Depending on whom you ask, such products give patients one more tool to ease side effects or false hope that a cancer-specific balm is more effective than a mild drugstore lotion.
It’s now easier than ever for cancer patients (and their relatives who come bearing presents) to find skin-care lines made specially for them. At least five brands are now sold in the gift shops of prominent hospitals, and some makers give free samples to oncologists for distribution to patients.
Lindi Skin started in 2003 with six products, after its founder, Lindy Snider, watched two friends endure cancer treatment. In March, its 13-piece line of creams and skin cooling wraps arrived in drugstores including the Duane Reade chain and the independent Minooka Pharmacy in Minooka, Ill. For the first time, the American Cancer Society is considering including Alra, a 20-year-old skin-care line, in its catalog, which is mailed to 1.2 million people.
As far as cancer side effects go, far greater attention has been paid to hair loss, fatigue and nausea than to the burns caused by radiation and dry skin caused by chemotherapy. But the tide is starting to turn. Northwestern University opened the Cancer Skin Care Program, one of the first centers of its kind, in 2006.
And oncologists and dermatologists are giving greater consideration to dermatologic issues, in part because new cancer-fighting drugs called targeted therapies can cause rashes so severe that some patients threaten to drop out if they are left untreated.
“There are more drugs that cause skin issues nowadays,” said Dr. David Decker, an oncologist at William Beaumont Hospital in Royal Oak, Mich. “Radiation has always caused problems, but there are new drugs that cause issues, so skincare has become more of a focus.”
That has created an opportunity for makers of cancer-specific balms to grab the attention of doctors who previously might have dismissed them. Lindi Skin has nine sales representatives to hand out samples to oncologists (and plans to add three more this year). Jean Soulios of Beverly, Mass., who has had breast cancer, distributes samples of her Jeans Cream, an aloe-and-vitamin-E balm for skin irritated by radiation or chemotherapy, to about 20 hospitals. (It is also now sold in about 75 stores.)
“Addressing skin care is not unreasonable,” said Dr. David F. Horne, an assistant clinical professor of dermatology at NewYork-Presbyterian/Weill Cornell. “The patient may have a tumor in their lung but the changes they’re seeing are in their skin.”
Some oncologists don’t wait until a rash or blotches develop. Instead, early in treatment, they recommend soothing body washes and creams to patients. For instance, Dr. David I. Rosenthal, the director of head and neck radiation research at M. D, Anderson Cancer Center in Houston, gives his patients samples of Lindi Skin Cooler Rolls and body lotion.
“It is my impression that these skin conditions that are cancer-treatment-related are neglected,” said Dr. Rosenthal, who sits on Lindi Skin’s medical advisory board but is not paid by the company. “They can cause discomfort for the patient and should be addressed proactively.”
Still, there’s no proof that any of the products designed for cancer patients calm or heal skin irritated by radiation or chemotherapy any better than over-the-counter products like Cetaphil or CeraVe, according to the oncologists, dermatologists and oncology nurses interviewed for this article. Even Dr. Rosenthal said that “there’s not been any scientific study to show that these products are superior in any way.”
Mimi Bartholomay, an oncology clinical nurse specialist at Massachusetts General Hospital Cancer Center, where the gift shop sells Lindi Skin and Jeans Cream, said she worries that cancer patients will think the hospital endorses them. (It doesn’t.)
“They’re marketing to a vulnerable population,” she said. “Cancer patients go through so many body image concerns and changes. They get scars. Their skin changes from radiation. Sometimes the chemotherapy causes rashes. Their hair can fall out. They’re going to try anything to look and feel better.”
Ms. Snider of Lindi Skin doesn’t think she’s taking advantage of cancer patients. “Most people, if they have a special need, they’re willing to buy a product,” she said. “It’s sort of like saying, ‘Why isn’t chemo free?’ Doctors who administer chemo make money on that. We need to afford to make these products. I’m trying to fill a need.”
Jeans Cream and Lindi Skin are packaged in a way that they wouldn’t seem out of place at Bloomingdale’s, but they also sell for department-store prices. Lindi’s body wash costs $20 for 8 ounces, and its face serum, $40 for 1 ounce. Seven ounces of Jeans Cream is $45.
Ms. Rosenthal, for one, can’t afford them. “Forty bucks,” she said, “is two co-pays to a doctor or four co-pays for my prescription drugs.” But she did like the Lindi line, finding it “excellent for hydrating my skin. I have a hard time tolerating even naturally scented products, but I have no problem with Lindi’s lavender scent.”
Alra, a three-product line developed by Henry Ott after his wife, Sarah, underwent radiation therapy for breast cancer, is far cheaper, $13 for vitamin-E-and-aloe cream.
Radiation can cause what looks and feels like a sunburn on the area the beam passes through to get to cancerous cells, and chemotherapy can make the skin and lips dry and itchy because it indiscriminately tries to damage all fast-growing cells, including skin cells.
Simple wound care should heal skin aggravated by either treatment, the dermatologists interviewed for this article said. They recommended washing the affected area gently, patting it dry, keeping it moist and bacteria-free with a petroleum-jelly product like Aquaphor, and covering it with gauze. “I say to patients, ‘You’ll have just as good as an outcome with standard wound care, rather than expensive products,’ ” said Dr. Horne of NewYork-Presbyterian.
But targeted therapies can be harder on the skin than radiation or chemotherapy, Dr. Decker and Dr. Rosenthal said. They attack tumor cells specifically instead of all cells and can cause very dry skin or an upper- or full-body rash.
Dr. Mario Lacouture, the director of Northwestern’s Cancer Skin Care Program, sometimes treats skin conditions caused by targeted therapies with prescription corticosteroids and antibiotics. He will soon begin a study of over-the-counter products to see which best ameliorate side effects of targeted therapies. (Lindi Skin gave a $65,000 contribution to his research.)
Dianne Dassa, of New York, 66, said that Lindi products helped heal her radiation burn and her psyche. While being treated for breast cancer, she used the Lindi body wash and serum, preferring them to the body wash and Aquaphor her radiologist suggested. When they arrived, Ms. Dassa said, “They were so beautifully packaged, I felt like I was getting a gift.”
Lindi Skin is the focus of this post on the [My] Style Blog section of My Style Files, an online style and fashion blog.
Did you know that 42% of Americans will be diagnosed with cancer? Startling, I know. Chances are, you are close to several people inflicted with the disease. Cancer patients undergo a lot. However, sometimes the health of their skin is overlooked. According to a new survey by CancerCare, skin-related side effects are a concern for most cancer patients who have undergone cancer treatment. The survey revealed that nearly 80% were concerned about the actual skin effects they experienced as a result of their treatment and how those side effects (irritation, rash and dryness) affected their quality of life.
Enter Lindi Skin. As you are already aware, May is skin cancer awareness month. It's the perfect time to highlight an amazing company with a big heart helping people deal with the skin-related side effects of chemotherapy and radiation. Lindi Skin is a collection of skin care products with a unique delivery system to protect against moisture loss. These products provide extreme hydration to skin that has been treated - or for those of us with sensitive skin. Lindi Skin products also utilize phenomenal anti-aging ingredients.
Of course Lindi Skin combines the latest medical information with innovative skin care ingredients to deliver one-of-a-kind products. But really, it's about putting control back into patients' lives. After all, they want to feel normal.
After two of her friends were diagnosed with cancer, encountering unbelievable skin problems, Lindy Snider felt compelled to get involved. With a background in sales and marketing in the sports and entertainment arena, Lindy finally gave into her passion. After a ton of research, focus groups and the formation a scientific advisory board, Lindi Skin was launched in 2003. A few products were launched at the Oncology Nursing Congress. Immediately, Lindy knew she was onto something with the incredible feedback of doctors, nurses and most importantly, patients.
It's not easy being a start-up company. However, I have never done anything more gratifying. It's so worth it.
In 2007, J.J. Cutler joined Lindi Skin to help take the brand to the next level. His background in consumer products and services in the healthcare industry of 10 years lends well to his role, devoting his time to medical centers, cancer centers, oncology nurses, retail stores and the website. Currently, 80% of national online sales come from doctor and nurse referrals. That speaks volumes.
Unfortunately, most beauty editors won't cover products for cancer patients, such as Lindi Skin. As a beauty editor myself, this doesn't make sense to me. For one, we can all benefit from a gentle skin care line aimed at providing hydration that happens to deliver anti-aging qualities. Second, as more and more of our population manages life with cancer, it's incumbent upon us to get the word out. If you haven't visited Lindi Skin online, please do so. And donate whatever and whenever you can to the American Cancer Society.
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