Treatment/
Drug Type | Drug Brand Name (generic name) | Adverse Skin Reaction | Skin Care Regimens |
| Epidermal growth factor receptor (EGFR) inhibitors |
- Iressa (Gefitinib)
- Erbitux (Cetuximab)
- Tarceva (Erlotinib)
- Vectibix (Panitumumab)
- Tykerb (Lapatinib)
- Combined EGFR/HER2 antagonists
|
- EFGR (Acne-like)rash
- erythema
- xerosis (dry skin)
- papules/pustules
- pruritus (itching)
- telangiectasia
- fissures
- alopecia
- discolored or bumpy nails
|
|
| Multikinase inhibitors |
- Gleevec (Imatinib)
- Sprycel (Dasatinib)
- Tasigna (Nilotinib)
- Nexavar (Sorafenib)
- Sutent (Sunitinib)
|
- Hand-foot syndrome
- xerosis (dry skin)
- subungual splinter hemorrhages
- acne-like rash
- pruritus (itching)
- facial erythema
- scalp dysesthesia
- skin discoloration
- bruising
- thinning of skin
|
|
| Alkylating agents |
- Myleran (Busulfan)
- Eloxatin (Oxaliplatin Melphalan)
- Temodar (Temozolomide)
- Paraplatin (Carboplatin)
- Thioplex (Thiotepa)
- Mustargen (Mechlorethamine)
- Leukeran (Chlorambucil)
- Zanosar (Streptozocin)
- Platinol (Cisplatin)
- Semustine (Methyl-CCNU)
- Endoxana (Cyclophosphamide)
- DTIC, DTIC - Dome (Dacarbazine)
- Ifex (Ifosfamide)
|
- Mucositis
- paronychia
- flushing
- xerosis (dry skin)
- pruritus (itching)
- facial erythema
- alopecia
- pigmented bands on nails and teeth
|
|
| Spindle inhibitors |
- Taxotere (Docetaxel)
- Texol (Paclitaxel)
- Navelbine (Vinorelbine)
- Camptosar (Irinotecan)
- Hycamtin (Topotecan)
- Velban (Vinblastine)
- Oncovin (Vincristine)
- Vepesid (Etoposide)
|
- Hand-foot syndrome
- dermatitis
- xerosis (dry skin)
- pruritus (itching)
- edema
- mucositis
|
|
| Antimetabolites |
- Fludara (Fludarabine)
- Leustation (Cladribine)
- Xeloda (Capecitabine)
- Clolar (Clofarabine)
- Depocyt (Cytarabine)
- FUDR (Floxuridine)
- Hyrdea (Hydroxyurea)
- Arrano (Nelarabine)
- Nipent (Pentostatin)
- Rheumatrex (Methotrexate)
- Purinethol (Mercaptopurine)
- Tabloid (Thioguanine)
- Adrucil (5-fluorouracil)
- Uftoral (Tegafur)
- Gemzar (Gemcitabine)
- Alimta (Pemetrexed)
|
- Edema
- pruritus (itching)
- xerosis (dry skin)
- facial flushing
- photosensitivity
- mucositis
- Hand-foot syndrome
|
|
| Antitumor antibiotics |
- Blenoxane (Bleomycin)
- Ellence (Epirubicin)
- Idamycin (Idarubicin)
- Mithracin (Plicamycin)
- Novatrone (Mitoxantrone)
- Cosmegen (Dactinomycin)
- Cerubidine (Daunorubicin or Rubidomycin)
|
- Rash (flagellate hyperpigmentation)
- pruritus (itching)
- xerosis (dry skin)
- Hand-foot syndrome
- mucositis
|
|
| Antiangiogenesis |
|
- Mucositis
- flushing
- sores on mouth or lips
- xerosis (dry skin)
|
|
| Corticosteroid hormones/other |
- Deltasone (Prednisone)
- Orasone (Prednisone)
- Prednicen-M (Prednisone)
- Liquid Pred (Prednisone)
|
- Bruising
- fungal infections (white patches in mouth, vagina)
|
|
| Hormones/aromatase inhibitors |
- Cytadren (Aminoglutethimide)
- Zevalin (Ibritumomab)
- Casodex (Bicalutamide)
- Herceptin (Trastuzumab)
- Eulexin (Flutamide)
- Faslodex (Fulvestrant)
- Bexxar (Tositumomab)
- Nolvadex (Tamoxifen)
- Femara (Letrozole)
- Zoladex (Goserelin)
- Lupron (Leuprolide)
- Megace ES (Megestrol Acetate)
|
- Edema
- angioedema
- erythema
- rash
- flushing
- hot flashes
|
|
| Radiation |
- External beam therapy
- External Beam Radiation
- External Radiation Therapy
- Novalis Tx®, Varian Medical Systems, Inc. and BrainLab, Inc. (Intensity modulated radiation therapy)
- Synergy S®, Elekta, Inc. (Intensity modulated radiation therapy)
- CyberKnife®, Accuray, Inc. (Intensity modulated radiation therapy)
- stereotactic radiosurgery (with gamma knife)
|
- Radiation dermatitis
- dry desquamation
|
|
